Distance from Tupelo, MS to Saint Louis, MO is 371Miles or 597 Km. You can get this distance about 5 hours 50 mins. If you want to planning travel with plane for 314 Miles or 505 Km, You can get this distance about 1 hours 10 mins .
A car with an average MPG will needs 17.18 gallons of gas to get the route between these points.
The estimated cost of gas to get between Tupelo, MS and Saint Louis, MO is $39.
During the route, an average car will release 336.59 pounds of CO2 to the atmosphere. Your carbon footprint is 0.91 pounds of CO2 per mile.
* Average US MPG used for calculations is 21.6 MPG.
* Average US gas price used for calculation is 2.27 per gallon.