Distance from Gainesville, FL to Florence, SC is 379Miles or 609 Km. You can get this distance about 5 hours 37 mins. If you want to planning travel with plane for 349 Miles or 561 Km, You can get this distance about 1 hours 14 mins .
A car with an average MPG will needs 17.55 gallons of gas to get the route between these points.
The estimated cost of gas to get between Gainesville, FL and Florence, SC is $39.84.
During the route, an average car will release 343.84 pounds of CO2 to the atmosphere. Your carbon footprint is 0.91 pounds of CO2 per mile.
* Average US MPG used for calculations is 21.6 MPG.
* Average US gas price used for calculation is 2.27 per gallon.