Best route map between Frederick, MD and Florence, SC. This route take about 440 Miles.
The distance and estimated time is placed on the right depending on the status of the road.
* You can see Frederick, MD and Florence, SC photos above. We provide this photos from Google Panoramio service.
* Frederick, MD weather as celsius: -4.5 °C
* Florence, SC weather as celsius: -1 °C
* Weather information on route, provide by Open Weather Map.
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